Final program
Key note speakers: Dennis Y.M. Lo, Howard S. Cuckle, Erik A. Sistermans
| 25th May | |
| Chairs: Dennis Lo, Howard Cuckle, Jasenka Wagner | |
| 9.00-10.00 | Y. M. Dennis Lo (Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong): Deciphering the origin of DNA in plasma: implications for non-invasive prenatal testing |
| 10.00-10.45 | Howard Cuckle (Faculty of Medicine, Tel Aviv University, Israel; Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, USA; School of Medicine, University of Leeds, UK): NIPT cost revisited |
| 10.45-11.00 | Break |
| Chairs: Erik A. Sistermans, Gordan Lauc | |
| 11.00-11.45 | Erik A. Sistermans (VU University Medical Center Amsterdam, the Netherlands): Introducing NIPT analysis in the Netherlands, a story of science and politics |
| 11.45-12.05 | Aleš Maver, Borut Peterlin (Clinical Institute of Medical Genetics, University Medical Centre Ljubljana): The role of genetic services in provision of NIPT |
| 12.05-12.30 | Ishraq Dhaifalah, Marek Godava (FETMED Olomouc, Czech Republic): NIPT and the clinical practice |
| 12.30-13.00 | Howard Cuckle (Faculty of Medicine, Tel Aviv University, Israel; Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, USA; School of Medicine, University of Leeds, UK): NIPT and the future need for traditional markers |
| 13.00-13.15 | Discussion |
| 13.15-14.15 | Lunch |
| Chairs: Zora Lasabova, Ishraq Dhaifalah | |
| 14.15-14.40 | Agnieszka Orzińska, Katarzyna Guz, Ewa Brojer (Institute of Hematology and Transfusion Medicine, Warsaw, Poland): Noninvasive diagnostics of blood group antigens in Polish pregnant women |
| 14.40-15.05 | Nikoletta Nagy, Marta Szell (Department of Medical Genetics, University of Szeged, Szeged, Hungary): Non-invasive screening alternatives for rare monogenic diseases |
| 15.05-15.30 | Zora Lasabová (Comenius University in Bratislava, Jessenius Faculty of Medicine in Martin, Slovakia): Our experience with non-invasive prenatal testing |
| 15.30-15.45 | Break |
| Chairs: Ilona Hromadnikova, Balint Nagy | |
| 15.45-16.10 | Balint Nagy (Department of Human Genetics, University of Debrecen, Debrecen, Hungary): The hidden treasure, miRNAs in the NIPT |
| 16.10-16.35 | Ilona Hromadnikova (Department of Molecular Biology and Cell Pathology, Third Faculty of Medicine, Charles University, Prague, Czech Republic): Circulating heat shock protein mRNA profiles in gestational hypertension, preeclampsia and fetal growth restriction |
| 16.35-17.00 | Peter Celec (Institute of Molecular Biomedicine, Comenius University, Bratislava, Slovakia): Is there a role for extracellular DNA in the pathogenesis of preeclampsia? |
| 17.00-17.20 | Ilona Hromadnikova (Department of Molecular Biology and Cell Pathology, Third Faculty of Medicine, Charles University, Prague, Czech Republic): First trimester screening of circulating C19MC microRNAs can predict subsequent onset of gestational hypertension |
| 17.20-17.40 | Discussion |
| 26th May | |
| Chairs: Peter Celec, Marta Szell | |
| 8.30-9.00 | Lieve Page-Christiaens (Reproductive & Genetic Health, Illumina, Inc.): Clinical Experience Results on Non-Invasive Prenatal Testing : Implications for Counseling and Choices |
| 9.00-9.30 | Maximilian Schmid (Roche): Perspectives on the future of NIPT |
| 9.30-9.45 | Maja Barbalić (Genom d. o. o. Zagreb, Croatia): Two years of Harmony Prenatal test in Croatia |
| 9.45-10.15 | Jessie Theuns (Multiplicom N.V., Niel, Belgium): Implementation of a decentralized lab solution for NIPT testing |
| 10.15-10.45 | Tomas Szemes (Geneton Ltd., Bratislava, Slovakia): The utilization of MiSeq platform for noninvasive |
| 10.45-11.00 | Break |
| Chairs: Hakan Savli, Agnieszka Orzińska | |
| 11.00-11.30 | Burcu Dartan-Karagozler (QIAGEN Germany / Inel): How to overcome the challenges in circulating nucleic acids workflows |
| 11.30-12.00 | Joseph V. Thakuria (Veritas Genetics, Danvers, MA, USA): myHealthyStart: a new paradigm in reproductive genomic health |
| Chairs: Feodora Stipoljev, Vida Čulić | |
| Selected abstracts presentations | |
| 12.00-12.10 | Martin Hynek, Filip Zembol, Ivona Marešová, Svatava Horáčková, Martina Bittóová, Monika Koudová, David Stejskal (Gennet, Prague, Czech Republic): Contingent cell-free DNA test in routine prenatal aneuploidy screening |
| 12.10-12.20 | Vida Čulić (Medical Genetics, Paediatrics Clinics, UHC Split): NIPD and importance of genetic counseling |
| 12.20-12.30 | Feodora Stipoljev, Kristina Crkvenac-Gornik, Sanda Huljev Frković, Romana Gjergja-Juraški, Bojana Brajenović-Milić (Cytogenetic Laboratory, Clinic of Obstetrics and Gynecology, Clinical Hospital „Sveti Duh“, Zagreb): Seven false-positive cases from noninvasive cell-free fetal DNA testing: data obtained from three referring centres in Croatia |
| 12.30-12.40 | Ivanka Bekavac Vlatkovic, Jasenka Wagner, Ana Vičić, Feodora Stipoljev (University Hospital „Sveti Duh“, Department of Obstetrics and Gynecology, Zagreb; Medical genetics laboratoty, Faculty of Medicine in Osijek ): Relationships between total and fetal cell free DNA, fetal characteristics and serum analytes in the first trimester of pregnancy |
| 12.40-12.50 | Priskin K, Pinter L, Jaksa G, Balogh D, Farkas K, Nagy N, Csűrös M, Széll M, Haracska L (Delta Bio 2000 Ltd. Szeged, Hungary): Quantitative MPS-based NIPT method using internal amplification control during library preparation |
| 12.50-13.00 | Orsolya Biro, Balint Nagy, Lucia Strieskova, Michaela Hyblova, Tomas Szemes (1st Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary; Human Genetics Department, University of Debrecen, Debrecen, Hungary): Identifying sub-chromosomal deletions and duplications by NIPT in congenital heart disease cases |
| 13.00-13.10 | Barbora Vlková, Marta Kalousová, Peter Celec (Institute of Molecular Biomedicine, Comenius University, Bratislava, Slovakia): Extracellular DNA in pregnancies with intrahepatic cholestasis |
| 13.10-13.20 | Orsolya Biró, Bálint Nagy, János Rigó Jr. (1st Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary; Human Genetics Department, University of Debrecen, Debrecen, Hungary): Identifying potential miRNA biomarkers for preeclampsia by systems biology approaches |
| 13.20-13.30 | Discussion |
| 13.30-13.45 | Balint Nagy (Department of Human Genetics, University of Debrecen, Debrecen, Hungary): Debrecen - City of flowers |
| 13.45-14.00 | Closing ceremony |